Abstract

This study was designed to describe the sleep profile in a cohort of children 5-15 y with idiopathic generalized epilepsy (IGE) using polysomnography (PSG) and Children's Sleep Habits Questionnaire (CSHQ) and Pittsburg Sleep Quality Index (PSQI). The controls included age- and gender-matched healthy controls. A total of 30 cases of IGE and matched 30 controls were enrolled in study. The global CSHQ score [58.8 (10.8) vs. 32.3 (4.1); p < 0.01] and PSQI score [2.4 (1.6) vs. 0.9(0.3); p < 0.01] was significantly higher among children with IGE as compared to controls. REM sleep duration was significantly lower and other parameters including AHI [2.8 (1.9, 4.6) vs. 2.6 (1.3, 2.9); p = 0.04], frequency of arousals [51.5 (36.7, 71.5) vs. 27 (24, 43); p < 0.01], percentage of oxygen desaturation > 4% [23.5 (8, 36.5) vs. 4 (2, 8); p < 0.01], were significantly higher among children with IGE when compared to controls. Children with IGE havesleep disturbances and alteration in sleep architecture. Theyshould be assessed and screened for sleep characteristics.

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