Abstract
Sleep Apnea Syndrome and Covid-19 Infection Correlation: Treated/Not Treated OSAS Patients Comparison
Highlights
Obstructive sleep apnea (OSA) is a common disorder characterized by upper airway caliber reduction during sleep, habitual and persistent snoring, every night for at least six months and repetitive episodes of nocturnal breathing cessation, partial or complete, due to upper airway collapse; each pause can last for a few seconds to a few minutes and they happen many times a night
Because of sleep apnea syndrome causes an upper airway inflammation [8,9], we ask if OSAS patients could take Covid infection easier, if there are variables that can affect the Apnea/Hypopnea index (AHI) at T1 time, if the presence of comorbidities affects the OSAS trend and if OSAS therapy is a protective factor for Covid infection
Sleep apnea syndrome causes an upper airway inflammatory condition, it is difficult to establish if that disease can promote Covid infection development
Summary
Obstructive sleep apnea (OSA) is a common disorder characterized by upper airway caliber reduction during sleep, habitual and persistent snoring, every night for at least six months and repetitive episodes of nocturnal breathing cessation, partial or complete, due to upper airway collapse; each pause can last for a few seconds to a few minutes and they happen many times a night. Hypopnea and apneas events make oxygen level decreasing, this is called hypoxemia [4,5] It causes cerebral, metabolic and cardiovascular diseases and some pathophysiological consequences such as respiratory effort and endothoracic negative pressure increased, sympathetic vegetative activation, sleep micro- awakening, intermittent hypoxemia, inflammatory processes [6]; it produces an alterated immunoregulation and respiratory instability during sleep [7]. Metabolic and cardiovascular diseases and some pathophysiological consequences such as respiratory effort and endothoracic negative pressure increased, sympathetic vegetative activation, sleep micro- awakening, intermittent hypoxemia, inflammatory processes [6]; it produces an alterated immunoregulation and respiratory instability during sleep [7] From this point the idea of this study starts. Because of sleep apnea syndrome causes an upper airway inflammation [8,9], we ask if OSAS patients could take Covid infection easier, if there are variables that can affect the Apnea/Hypopnea index (AHI) at T1 time, if the presence of comorbidities affects the OSAS trend and if OSAS therapy is a protective factor for Covid infection
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