Skrining karcinoma grlića materice - prošlost, sadašnjost i pogled u budućnost

Abstract

Cervical cancer is the fourth most common carcinoma in women globally, following breast, lung and colon cancer. Primary prevention (vaccination) and secondary prevention (organised screening) in developed countries have made a significant difference in the structure of morbidity, as well as mortality from this disease, compared to undeveloped countries. The primary objective of cervical cancer screening is identification of abnormal epithelial cells that are likely to progress into invasive carcinoma (CIN II + and AIS) and that require surgical treatment, which reduces cervical cancer incidence and mortality. Secondary objective of screening is diagnosing early stages of invasive carcinoma (MIC) which also decreases cervical cancer morbidity and mortality. Cervical cancer screening strategy differs in different parts of the world and needs to be adapted to the methods that are available and reliable in the given country, and that allow for the best possible organisational arrangements and development of the infrastructure for cancer screening implementation and quality assurance, in line with specific human and financial resources available to the country