Abstract
An improved optical coherence tomography (OCT) technique called line-field confocal OCT (LC-OCT) has been developed for high-resolution skin imaging. Combining the principles of time-domain OCT and confocal microscopy with line illumination and detection, LC-OCT acquires multiple A-scans in parallel with dynamic focusing. With a quasi isotropic resolution of ∼ 1 μm, the LC-OCT images reveal a comprehensive structural mapping of skin, in vivo, at the cellular level down to a depth of ∼ 500 μm. LC-OCT images of various skin lesions, including carcinomas and melanomas, are found to well correlate with histopathological images. LC-OCT could significantly improve clinical diagnostic accuracy, while reducing the number of biopsies of benign lesions.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
