Skin Grafting for Full-Thickness Burn Injury

Abstract

skin integrity; however, other conditions such as trauma, circulatory disorders, and radical surgery may also result in partial or full-thickness damage to the skin. Damage to the skin is frequently defined in terms of partialor full-thickness injury. Partial-thickness injuries are further differentiated into superficial and deep categories. Superficial partial-thickness injuries damage the epidermis, which is made up of keratinized fiber that is continuously replenished from underlying desquamated cells migrating to the superficial layer. This keratinized layer forms a protective wall between the host and the environment. If this wall is stripped away, the underlying cells rapidly replace it. This type of injury commonly occurs with first-degree burns, such as sunburn.