Abstract
The thickness and collagen content of forearm skin were measured in 13 patients with systemic sclerosis, in 8 of whom the forearm skin was found to be clinically affected by the disease. No increase in skin thickness or its collagen content was found. The thickness and collagen content of the clinically affected forearm skin were usually decreased and collagen density was normal. It is concluded that the clinical impression of thickness and toughness is due to binding down of the skin to deeper structures. The similarity of atrophic morphoea and systemic sclerosis is discussed.
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