Abstract
Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy and is characterized by slow growth and an indolent biological behavior. Papillary thyroid microcarcinoma is the PTC with the maximum size of the tumor <1cm, considered the most indolent form of thyroid cancer. PTC is usually metastasizes in cervical lymph nodes, lungs and bones and, less commonly, in brain or liver. Skeletal muscle metastases from PTC are extremely rare, a retrospective review of the literature revealed only 13 case reports. Among them, six cases are solitary skeletal muscle metastases, and seven are multiple metastases, most of them being associated with lung lesions. It seems that PTC is prone to metastasizing to the erector spinae and thigh muscles groups with unique cases located in trapezoid, biceps, deltoid, gastrocnemius and rectus abdominis muscles. Although extremely rare, one must bear in mind the fact that muscle metastasis from PTC is possible, and that is the reason we would like to discuss the existing clinical cases and to add a unique case of solitary skeletal muscle metastasis from papillary microcarcinoma.
Highlights
Papillary thyroid cancer (PTC) is the most common thyroid malignancy [1], and it is defined as a malignant epithelial tumor with evidence of follicular differentiation and a series of specific nuclear features [2]
The other cases presented from the literature had a similar therapeutic approach: radical surgery whenever was possible, radioiodine, in one case being added to systemic therapy with thyrosine kinase inhibitors, in the study of Mohapatra et al As a 2020, special mention, despite the late recurrence of the disease, presence of distant metastasis5 and
The epidemiological aspects thyroid and their identification could have a significant impact on patient management
Summary
Papillary thyroid cancer (PTC) is the most common thyroid malignancy [1], and it is defined as a malignant epithelial tumor with evidence of follicular differentiation and a series of specific nuclear features [2]. Papillary thyroid microcarcinoma is the PTC with the maximum size of the tumor
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