Abstract
One hundred and eighty chick embryos were studied for the presence of skeletal malformations after administration of mitomycin C at 72, 96 and 120 hours of incubation. Axial skeleton defects included those of ribs, vertebrae, beak and crania. Appendicular skeletal defects were mainly confined to the lower limbs e.g. absence of phalanges, bent and shortened femur, fibula, tibia and metatarsus, in that order. Absence of phalanges and curved scapulae were noted in the upper limbs. The length of femur, tibia and metatarsus was significantly reduced (P less than 0.001) compared with the corresponding controls especially in the group treated at 96 h.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
