Abstract
A 39-year-old female patient with fibromyalgia and complaints of xerostomia was referred to a dental surgeon because of the suggestion of Sjogren Syndrome (SS). She had major salivary gland scintigraphy suggestive of parotid gland obstruction. She also had a positive serologic test for anti-Ro but negative tear break-up and Schirmer tests. Minor salivary gland biopsy was performed, with 7 glands collected. Histologic examination showed the presence of 5 lymphocytic foci (each with ≥ 50 lymphocytes) around ducts (some dilated) or blood vessels, adjacent to normal appearing acini. Fibrosis, adipose infiltration, germinal center, and lymphoepithelial lesion were not observed. The whole gland tissue measurement was 21 mm², resulting in a focal score of 1 (1 focus/4 mm2), which is considered a focal lymphocytic sialadenitis histologically compatible with SS. The final diagnosis of SS was established based on the combination of histology, clinical, and serology results. The patient is under treatment with a rheumatologist.
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