Abstract
Introduction: Sjögren’s syndrome (SS) is a chronic inflammatory auto-immune disease of the exocrine glands which incidence increases with age. Sex ratio is 9.9 female for 1 male. Observation: A 67-year-old female patient presented for xerostomia leading to major functional impairment. The medical history of the patient was pulmonary sarcoidosis, with join and adenoid involvement, considered as cured; left partial parotidectomy, with a diagnosis of acinous carcinoma, followed 7 years later by a total parotidectomy due to tumor recurrence, and followed by external radiotherapy (70 Gy). Arterial hypertension, hypothyroïditis and diabetes mellitus were also noticed. She reported xerostomia and xerophtalmia. Seric anti-SSA antibodies were positive and histologic findings were compatible with SS. Commentaries: Despite other co-morbidities, the diagnosis was hidden by previous parotidectomy and cervical radiotherapy. Thus, SS should not be underdiagnosed in patients with complex medical history.
Highlights
A 67-year-old female patient presented for xerostomia leading to major functional impairment
The diagnosis is made on ocular dryness, mouth dryness, histologic features with focal lymphocytic sialadenitis, salivary alterations on scintigraphy and specific auto-antibodies
Previous head and neck radiotherapy or parotidectomy may interfere with the clinical presentation and complicate the diagnosis [2]
Summary
Sjögren syndrome hidden by previous parotidectomy and cervicofacial radiotherapy Aline Desoutter, Angélique Colin, Anne-Gaëlle Bodard1,*. Sex ratio is 9.9 female for 1 male. Observation: A 67-year-old female patient presented for xerostomia leading to major functional impairment. The medical history of the patient was pulmonary sarcoidosis, with join and adenoid involvement, considered as cured; left partial parotidectomy, with a diagnosis of acinous carcinoma, followed 7 years later by a total parotidectomy due to tumor recurrence, and followed by external radiotherapy (70 Gy). Commentaries: Despite other co-morbidities, the diagnosis was hidden by previous parotidectomy and cervical radiotherapy. SS should not be underdiagnosed in patients with complex medical history
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