Abstract
A patient suffering from rheumatoid arthritis and bilateral parotid and submaxillary gland swellings was followed for 5 years. During this time samples of parotid saliva (when available) and serum were tested by paper electrophoresis and immunoelectrophoresis. The findings were consistent with other data obtained on patients with Sjögren's syndrome except that no serum IgM immunoglobulin could be detected. Because of the glandular enlargements, radiation was directed first to the right side and, 1 year later, to the left side. The clinical data obtained in this study indicate that radiation restores enlarged glands to normal size and enhances the flow of saliva. Biochemical investigations reveal some improvement in serum and salivary patterns within 2 years after radiation. Four years after therapy the data suggest a remission of the disease and the appearance of IgM immunoglobulin in the serum.
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