Abstract
Peaceful coexistence with the infected host, commonly not causing clinical symptoms, is a frequent but poorly understood effect for many human pathogens, including Plasmodium falciparum.1 The continuous production of gametocytes (the transmissible parasite stage) by persisting P falciparum in individuals with asymptomatic infections possibly constitutes a primordial source for transmission. As the drive towards elimination intensifies, the following question arises: is there added benefit to identifying and treating asymptomatic infections to interrupt transmission?2
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