Siyanoakrilat ile Safen Ven Embolizasyonunda Ortalama Trombosit Hacmi ve Trombosit Sayısının Değişimi

Abstract

Background: In the present study, it is aimed to determine the intervention-related change in the mean platelet volume (MPV) and platelet count in saphenous vein embolization performed using cyanoacrylate in chronic venous stasis and varicose treatment, as well as explaining the possible venous thromboembolism events. Methods: 60 patients involved in the present study were selected from the patients, who had varicose and chronic venous stasis and who applied to the Cardiovascular Surgery Polyclinic of Medical Faculty of Adiyaman University. The files of patients undergone saphenous vein embolization using CA were performed digitally and their USG and laboratory results were analyzed. Among 437 patients, 60 patients’ undergone hemogram and biochemical examination before and after the intervention were involved in the present study. The preoperative (pre-op) and postoperative (post-op) platelet counts and mean platelet volumes of the patients were analyzed. Results: When compared to the pre-op period, no significant change was observed on 1 st post-ophour and 1 st post-op month (p ˃ 0.05), however the MPV value observed on the 3 rd post-op day was significantly higher than the pre-op period (p ˂ 0.05). The MPV value observed on the 3 rd post-op day was statistically higher than on 1 st post-op hour (p ˂ 0.05) and the MPV value observed on the 1 st post-op month was statistically significantly lower than on 3 rd post-op day (p ˂ 0.05). Conclusion: MPV did not significantly increase from the normal values on the 1 st postoperative day, whereas it significantly increased on the 3 rd postoperative day. Assuming that MPV is related with the increasing thrombogenicity, it can be stated that the saphenous vein embolization by using CA that is one of the minimally invasive methods used in varicose treatment may cause thromboembolic events in the early pre-op period (in the first week).