Abstract
Successful cancer treatment relies on understanding its etiology and the early detection of symptomatic patients. The identification of single nucleotide polymorphisms (SNPs) shared between distinct cancers can assist in furthering our understanding and serve as possible biomarkers. To investigate this objective, whole genome sequencing data were obtained from the Sequence Read Archive and then analysis pipelines constructed to map the sequences against chromosomes one and ten followed by indexing and variant calling. The chromosome one SNPs rs1418729588, rs1248545208, rs879148104 and the chromosome ten SNPs rs1321310328, rs1458969220, rs1836976520 were found to be shared by 7 different cancers that ranged from breast to prostate cancer. Our analyses identified cross-cancer SNPs that lay the foundation for future etiological studies and suggest that different cancers share common SNPs that may serve as suitable biomarkers.
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