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Abstract
BACKGROUND AND AIM: Chronic liver disease leads to reduction in health-related quality of life, particularly functional capacity. The data about the use of Six Minute Walk Test (6MWT) among cirrhotic patients are limited. The current study was done to evaluate the use of 6MWT in patients with HCV related chronic liver disease for assessing the functional capacity and to determine the correlation between the 6MWD and severity of chronic liver diseases. METHODS: This analytic cross-sectional study was carried out on 20 healthy volunteers (Group I), 40 HCV patients with early liver disease (Group II), and 40 HCV patients with liver cirrhosis (Group III). Six minute walk distance (6MWD) was calculated. RESULTS: The mean 6MWD was significantly lower in Groups II and III (325.8 ± 56.65 meter, and 131.79 ± 43.40 meter) compared to that of Group I (359.91 ± 38.63 meter) (p 0.05). CONCLUSIONS: Six-minute walk test is a reliable indicator to measure the functional capacity for patients with HCV related chronic liver diseases.
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