Abstract
The site of absorption of ascorbic acid by the small intestine was studied in vivo in guinea pigs, normal and hypophysectomized rats after oral application of 14C-ascorbic acid. A species-specific difference was revealed. The site of absorption in the guinea pig was located in the duodenal and proximal small intestinal wall, whereas the rat showed highest absorption in the ileum. Hypophysectomy in rats caused a shift of the absorption site from the ileum to the jejunum. No absorption was observed in the duodenum and ileum. A regulatory role of the pituitary gland in the absorption of ascorbic acid by the small intestine is discussed.
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Schedule a callMore From: Biochemical and biophysical research communications
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