Abstract
Radioactive histidine was used to investigate the place of synthesis of muscular carnosine. In rats with the liver functionally excluded synthesis of muscular carnosine by the inclusion of the radioactive amino acid progresses rapidly. Renovation of the dipeptide took place on both hepatectomized and nephrectomized animals. From the data gained the conclusion can be made that liver, kidneys and gastrointestinal tract do not participate in the synthesis of carnosine, its formation taking place in the muscular tissue.
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