Abstract
Umbilical metastasis is one of many characteristic signs of extensive neoplastic disease. It suggests advanced distant metastasis and is associated with poor prognosis; mean survival is approximately 10–12 months, although long-term survival has been reported, but only in the presence of a solitary metastatic umbilicus nodule. Sister Mary Joseph's nodule has traditionally been considered a sign of ominous prognosis (survival of 10 months on average) and suggests therapeutic abstention. We present such a case with a detailed review of the literature.
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