Abstract

Graft-versus-host disease (GVHD) remains a major complication of allogeneic haemopoietic stem cell transplantation (HSCT) and is one of the main causes of non-relapse mortality and poor quality of life. Treatment of GVHD is associated with long-lasting exposure to immunosuppressive treatment and related morbidity, therefore GVHD prevention is crucial to improve outcomes after transplantation.

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