Abstract
By nature, cancer cells are the toughest cells against any treatment. The various available therapies would be much more effective at much lower dose if siRNA against the therapeutic resistance could be identified and successfully codelivered by nanocarriers such as polymer conjugation, micelles, liposomes, solid lipid nanoparticles, nanohydrogels and dendrimers. Cancer is a significant health problem world wide. The death rate of cancer among the various diseases was 23.3% in the USA in 2010 and 30.0% in Singapore in 2011. Patients with cancers that are detected at later stages have a lower 5 - year relative survival (23.3% for breast cancer, 11.7% for colon cancer and 3.6% for
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