Abstract
Detection of volatile organic compounds (VOCs) in human breath to diagnose lung cancer is becoming an important method for widespread screening due to its convenient, rapid and low cost advantages. In this paper, experimental evidence for the detection of both polar and nonpolar VOCs molecules by organic materials functionalized single-walled carbon nanotubes (SWNTs) was investigated. To develop a high-selectivity SWNTs biosensor, nonpolymeric organic materials, tricosane (C 23H 48) and pentadecane (C 15H 32) were coated on the single-walled carbon nanotubes (SWNTs) and the prepared device was exposed to representative VOCs polar molecule 1,2,4-trimethybenzene (TMB) and nonpolar molecule decane separately. The results show that the resistance changes of SWNTs biosensor increased to 2.3% for decane and 7.2% for TMB after being functionalized by C 23H 48; meanwhile, the variation of 3.3% for decane and 5.1% for TMB was observed by C 15H 32-functionalized SWNTs. The results present that C 23H 48-functionalized SWNTs show pronounced sensitivity toward polar VOCs molecules, which can donate electrons to the SWNTs after being absorbed. This research is a further step toward the development of a simple and noninvasive diagnostic tool for the widespread screening of lung cancer via breath analysis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Physica E: Low-dimensional Systems and Nanostructures
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
