Single-Center Experience of Surgical Treatment of Primary Retroperitoneal Tumors.

Abstract

This study is an evaluation of surgical treatment results of primary retroperitoneal tumors. In Samara Regional Clinical Oncology Dispensary, from 2008 to 2015, the treatment of 187 patients (53 men and 134 women) was conducted. One hundred fifteen patients got tumor removal within the healthy tissue (R0), and 61 patients went through complete resection of tumor with wide margins (R0). Complete resection of tumor with wide margins (R0) with preoperative tumor vessel embolization was performed in 11 patients. According to the histological examination, malignant retroperitoneal tumor was detected in 85 patients (48.4%); in most cases it was presented by various forms of sarcoma. A benign tumor was diagnosed in 71 patients (40.3%), fibrolipomas (17.1%), and neurofibromas (12.5%). The diagnosis of 20 patients needs subsequent clarification, as mesenchymal tumor (6.2%) and histiocytoma (5.1%) were diagnosed. Short-term results of surgical treatment for the group, where complete resection of tumor with wide margins was performed: intraoperative blood loss 410.91 + - 113.31(ml), operation time 185.15 + -32.49(min); postoperative complications 10 (16,4%); mortality 3 (4,9%); LOS 23,14± 6,31; for removal of the tumor within healthy tissues: intraoperative blood loss 281.33 + -110.94 (ml), operation time 58.33 + -27.14(min) postoperative complications 7 (6,08%); mortality 2 (1,74%); LOS 6,98 ± 4,83; (t = 279, p = 0,015). For patients who went through preoperative tumor feeding vessel embolization, intraoperative blood loss was 121.33 ± 27.94 (ml), time of operation 43.13 ± 16.11 (min), postoperative complication 1 (4.5%), mortality 0 (0%), and length of stay 12.72 ± 1.49. After the complete resection of tumor with wide margins, intraoperative blood loss, operation time, the number of postoperative complications, and postoperative LOS were significantly greater in comparison with the group of patients where the tumor was removed within healthy tissues. The method of preoperative embolization of the tumor feeding vessels can reduce intraoperative blood loss, the time of operation, and the number of postoperative complications.