Abstract
Single-case design (SCD), also known as single-case experimental design, single-subject design, or N-of-1 trials, refers to a research methodology that involves examining the effect of an intervention on a single individual over time by repeatedly measuring a target behavior across different intervention conditions. These designs may include replication across cases, but the focus is on individual effects. Differences in the target behaviors and individuals studied, as well as differences in the research questions posed, have spurred the development of a variety of single-case designs, each with distinct advantages in specific situations. These designs include reversal designs, multiple baseline designs (MBD), alternating treatments designs (ATD), and changing criterion designs (CCD). Our purpose is to describe these designs and their application in behavioral research. In doing so, we consider the questions they address and the conditions under which they are well suited to answer those questions.
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