Abstract

Acoustic tweezers for microparticle non-contact manipulation have attracted attention in the biomedical engineering field. The key components of acoustic tweezers are piezoelectric materials, which convert electrical energy to mechanical energy. The most widely used piezoelectric materials are lead-based materials. Because of the requirement of environmental protection, lead-free piezoelectric materials have been widely researched in past years. In our previous work, textured lead-free (K, Na)NbO3 (KNN)-based piezoelectric ceramics with high piezoelectric performance were prepared. In addition, the acoustic impedance of the KNN-based ceramics is lower than that of lead-based materials. The low acoustic impedance could improve the transmission efficiency of the mechanical energy between acoustic tweezers and water. In this work, acoustic tweezers were prepared to fill the gap between lead-free piezoelectric materials research and applications. The tweezers achieved 13 MHz center frequency and 89% −6 dB bandwidth. The −6 dB lateral and axial resolution of the tweezers were 195 μm and 114 μm, respectively. Furthermore, the map of acoustic pressure measurement and acoustic radiation calculation for the tweezers supported the trapping behavior for 100 μm diameter polystyrene microspheres. Moreover, the trapping and manipulation of the microspheres was achieved. These results suggest that the KNN-based acoustic tweezers have a great potential for further applications.

Highlights

  • The theoretical of acoustic radiation force (ARF) calculation were illustrated in our previous work [25]

  • The piezoelectric response d33 of KNN-based textured ceramics is 319 pC/N, which are slightly lower than 585 pC/N for PZT-5H ceramics and much higher than 49 pC/N for LN single crystals

  • Because of the high sensitivity and board −6 dB bandwidth, the KNN-based acoustic tweezers can be excited under a large range of frequency

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Summary

Introduction

Non-contact manipulation for microparticles has attracted attention in the biomedical engineering field [1,2]. The most widely employed methods for non-contact manipulate microspheres and cells are optical tweezers [3,4]. There are several limitations for the use of optical tweezers. The optical tweezer can only be applied on optically transparent objects [1,5]. The trapping force is weak (at piconewton range) and the optical tweezer can only handle small objectives at a level of several micrometers or nanometers [5,6]. For bio-samples such as cells or bacteria, Micromachines 2022, 13, 175.

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