Abstract
Challenges in mandibular bony defect reconstruction still exist. The use of compacted autogenous particulate corticocancellous bone, together with a human humerus allograft presents an exciting opportunity to simplify the reconstruction of such defects. This is especially the case when the surgery may be done in one stage via an intra-oral approach. We present a case where all of the above have been incorporated for the reconstruction of the mandible.
Highlights
The cellular biology of bone healing is an ongoing topic for research
We revisit the concept of making use of an allogenic carrier in conjunction with the use of particulate corticocancellous bone (PCCB) for the reconstruction of mandibular bony defects
An allogenic demineralised humerus (Bone SA, Bramley, Johannesburg, South Africa) was used as a conduit for a compacted autogenous PCCB graft, harvested from the anterior iliac crest. This bone conduit was secured to the reconstruction plate (Figure 3) and the intra-oral access closed in two layers
Summary
The cellular biology of bone healing is an ongoing topic for research. Whilst it is understood that several growth factors interact with the cells of bone, the exact understanding of how this works remains an enigma. The use of allogenic bony cribs as a graft carrier has been reported in several studies [4,5,6]. These patients invariably require ablative surgery to render them disease free, but the subsequent reconstruction of the mandible remains challenging, when trying to select appropriate techniques and graft material.
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