Abstract

Vaccine research is supported by related fields like microbiology, biochemistry, and immunology. These lead to development of new vaccines for immunization of many diseases. In the pipeline there are more than 500 vaccines which are being extended to some form of peanut allergy, coronary artery diseases, cervical cancer, blindness, gastric ulcers, diabetes etc. New Vaccines against HIV, TB and Malaria are developing by researchers are still under development process because knowledge in some other areas are also important. Many traditional vaccines require multiple injections to provide effective patient protection these lead to costly and inconvenient regimen which gives a idea about single shot vaccines. The single shot vaccines can provide protection with only one injection for curing diseases1. During the development and manufacturing process of single shot vaccines the complex factors must be controlled for a significant influence on efficacy of immune response. Single shot vaccination concept is widely applicable to different types of antigens and vaccines. In future the research is required to know the adjuvants influence and release characteristics in different vaccination regimens.

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