Abstract
Here, we describe the first patient treated by single session robotic radiosurgery for low risk prostate cancer. The initial PSA of this 70-year-old patient was 5.05 ng/dl and transrectal biopsy confirmed a Gleason score 3+3=6 tumor. The patient refused a standard surgical and conventional radiation treatment. The combined choline PET/CT before treatment did not show any additional tumor locations and MRI excluded prostate capsule infiltration. Robotic radiosurgery was offered upon the patient's request as an individual treatment attempt. After ultrasound-guided transrectal fiducial implantation, a highly conformal treatment plan was generated and the patient was treated in April 2008 with 19 Gy to the 70% isodose in a single session. The treatment was tolerated very well with the minor dysuretic symptoms during the first two weeks after the procedure. The PSA continuously dropped in the following years and measured 0.07 ng/dl in July 2014. During this period, no significant clinical symptoms were detected, and the patient experienced no rectal or urinary toxicity. This is the first published patient treated with single session prostate radiosurgery, and we believe a prospective trial is warranted to investigate further the options of this attractive treatment concept for low-grade prostate cancer patients.
Highlights
The use of hypofractionated CyberKnife stereotactic radiotherapy as treatment for early-stage prostate cancer has been described recently [1,2,3,4,5]
We describe the first patient treated by single session robotic radiosurgery for low risk prostate cancer
No significant clinical symptoms were detected, and the patient experienced no rectal or urinary toxicity. This is the first published patient treated with single session prostate radiosurgery, and we believe a prospective trial is warranted to investigate further the options of this attractive treatment concept for low-grade prostate cancer patients
Summary
The use of hypofractionated CyberKnife stereotactic radiotherapy as treatment for early-stage prostate cancer has been described recently [1,2,3,4,5]. Assuming that α/β is that low and the underlying technology can achieve a precise targeting of the prostate by image-guided organ tracking, the ultimate goal for patient comfort would be to administer only a single fraction of. How to cite this article Muacevic A, Fuerweger C, Wowra B, et al (August 22, 2014) Single Session Robotic Radiosurgery for a Patient with Low Risk Prostate Cancer. We present a six-year follow up after single session image-guided robotic radiosurgery for a patient with low risk prostate cancer. The planning CT and MRI scans were done with a Foley catheter in place to define the course of the urethra through the CTV, to potentially give more stabilization to the prostate and to allow the bladder to empty during the course of treatment. There was no rectal or other toxicity in the follow-up period
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