Single photon emission computed tomography of reversible magnetic resonance imaging abnormalities of deep cerebral venous thrombosis accompanied with malignant glioma

Abstract

Background Deep cerebral venous thrombosis with reversible MRI findings in bilateral thalamus have been scarcely described in the literature, but none mentioned the SPECT findings such as in our case. Case Description A 43-year-old woman presented with cerebral venous thrombosis accompanied with malignant glioma. T 2- and diffusion-weighted MRI showed high intensity with a mass lesion in the left frontal lobe and mild high and high intensity in the right frontal lobe, parietal lobe, and bilateral thalamus. Cerebral angiography showed occlusions of the SSS and the DCVs. Furthermore, the initial SPECT showed apparent hypoperfusion in the same lesions on MRI. After the treatment involving infusion therapy and surgery, she recovered with a mild cognitive deficit. Although the repeat T 2- and diffusion-weighted MRI revealed the disappearance of high intensity, the repeat SPECT showed the persistent hypoperfusion in the infarcted lesions. Conclusion There might be a discrepancy between MRI and SPECT findings of the reversible case of DCVT, and SPECT also could be useful for the evaluation of the amelioration of DCVT.