Abstract

Post Mastectomy Pain Syndrome (PMPS) is a common postoperative condition for breast cancer, but has been ignored. The aim of this study was to investigate the prevalence of PMPS and the risk factors in women submitted to surgical treatment for breast cancer. The study included 532 postoperative breast cancer patients in a hospital for five consecutive years period, of whom 473 were considered eligible and included in the study. A total of 420 people completed a questionnaire survey, which revealed that 152 (36.2%) had ever suffered from PMPS and 18 (11.8%) sought treatment. Of the patients with PMPS, 34 (22.4%) had a history of chronic pain. Patients with PMPS were younger than patients without PMPS (50.5 ± 10.4 vs 53.5 ± 11.1). Univariate analysis showed that age, history of chronic pain, tumor staging, number of lymphadenectomy were significantly different between the two groups. Multivariate analysis shows that age and history of chronic pain were independent risk factors. The incidence of PMPS in postoperative breast cancer patients can reach 36.2%, and age as well as previous history of pain are independent risk factors for PMPS. The combination of prevention and treatment may be an effective way to reduce PMPS.

Highlights

  • Breast cancer is the most frequently diagnosed cancer globally and the leading cause of cancer-related death in women[1]

  • The aim of this study was to investigate the prevalence of Post Mastectomy Pain Syndrome (PMPS) and the risk factors in women submitted to surgical treatment for breast cancer

  • The vast majority of which were total mastectomy (96.4%); Excision of pectoralis major and/or pectoralis minor in 10 cases (2.4%); Four patients underwent a second operation in six years; The number of patients with PMPS was 152 (36.2%)

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Summary

Introduction

Breast cancer is the most frequently diagnosed cancer globally and the leading cause of cancer-related death in women[1]. PMPS seriously affects the physiological, psychological and quality of life of breast cancer patients[6], and these patients are a large group and should attract our attention. It has been decades since the first case of PMPS was reported[7], and early studies underestimated the incidence of PMPS for a variety of reasons. Due to the differences in race, disease prevalence, surgical techniques, and timing of surgery, it is necessary to study the prevalence and risk factors of PMPS in China. The aim of this study was to investigate the prevalence of PMPS and the risk factors in women submitted to surgical treatment for breast cancer

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