Abstract
Several clones encoding for a peptide similar to insulin-like growth factor protein binding (IGFBP) were found in a Litopenaeus vannamei hemocytes cDNA library. Although IGFBP is constituted by two well defined domains (IB and tyroglobulin) joint by a flexible region; the shrimp transcript encoding only for the IB domain as confirmed by Northern analysis. The expression of this, single IB domain (SIBD)-containing protein is modified by bacteria inoculation suggesting a role in immune response. In addition, shrimp SIBD protein seems to be the common ancestor for the IGFBP superfamily.
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More From: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics
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