Abstract
In 1958, attention was focused on griseofulvin, the first orally administered chemotherapeutic agent effective against dermatophyte infections. The clinical trials 1-10 thus far reported leave little doubt as to the curative effect of this antibiotic against tinea capitis, even those cases caused by Microsporum audouini. Little is known, however, concerning the optimal dosage. For example, Blank and Roth 1 treated two cases of M. audouini tinea capitis with daily dosages of 1-2 gm. for approximately four weeks. Sternberg et al. 8 reported the clinical cures of 18 patients with tinea capitis due to M. audouini in three to nine weeks after any of a wide variety of dosages. Kirk and Ajello 3 treated patients with 3 to 17 mg. per pound of body weight daily, some of these for four weeks, others longer. These authors felt that in general they observed better results in those patients who received at least
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
