Abstract
External beam radiotherapy is frequently applied for palliative treatment of painful bone lesions with a variety of fractionation schemes. There is a continuous interest to administer only 1 or a few dose fractions for inducing pain relief. A review of the literature was made with the aim to determine whether a treatment can be deduced that is simple and effective. The linear-quadratic (L-Q) concept was applied to compare therapy schemes which each other for the iso-effect pain relief. Single-dose and fractionated radiotherapy resulted in partial or complete pain relief in about 80% of the patients. Complete responses have been observed in about 43% of the patients. For patients responding to treatment, the duration of pain relief is at least 3 to 4 months with reported duration of up to 1 year or even longer. Based on this review of literature data concerning randomized trials a treatment with a single dose of 8 Gy is effective for inducing pain relief.
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Schedule a callMore From: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
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