Abstract
Seventy-six adults with either arthritis or asthma have been treated with a single daily dose of up to 15 mg of prednisone for from one to 19 years (average, 3.7 years). Although blunting of the serum cortisol response to adrenocorticotropic hormone occurred in some, no complete pituitary suppression occurred until a larger dose was given. The single daily dose can be given in either the morning or evening with no notable difference in serum cortisol response to adrenocorticotropic hormone. Only minor side effects occurred infrequently. This therapeutic regimen should be useful in other diseases for which steroid therapy is indicated. Patients receiving a single daily dose should receive supplemental corticosteroids during periods of unusual stress, eg, a major surgical procedure. ( JAMA 241:2721-2723, 1979)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: JAMA: The Journal of the American Medical Association
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
