Single-centre Experience Comparing PBI to WBRT and the Effects on Volume of Breast Tissue Treated, Heart and Lung Dosimetry

Abstract

Purpose: The IMPORT-LOW trial demonstrated non-inferiority of partial-breast radiotherapy (PBI) compared with standard whole breast radiotherapy (WBRT) with regards to local relapse in patients with early breast cancer with equivalent or fewer late normal tissue effects at 5 years [1]. This led to UK practice change, with selected low-risk patients offered PBI [2]. We aim to evaluate our single-centre experience by comparing volume of breast tissue treated, heart and lung dosimetry in patients treated with PBI compared to WBRT.