Single cell stimulus selectivities in the macaque middle superior temporal sulcus body patch, defined by fMRI

Abstract

Event Abstract Back to Event Single cell stimulus selectivities in the macaque middle superior temporal sulcus body patch, defined by fMRI Ivo D. Popivanov1*, Jan Jastorff1, Wim Vanduffel1, 2, 3 and Rufin Vogels1 1 KU Leuven, Belgium 2 MGH Martinos Center, United States 3 Harvard Medical School, United States Single-cell and fMRI studies in non-human primates have shown responses to faces and body parts in the inferotemporal cortex. In the present study we recorded single-cell spiking and local field potential (LFP) activity in and surrounding an fMRI-defined body patch to determine the selectivity for animate and inanimate objects. The stimuli were 100 monochrome images, grouped in 10 classes (10 images each): headless monkey and human bodies, 2 sets of control objects (matched for each of the body classes), monkey and human faces, 4-legged mammals, birds, fruits and sculptures (by H. Moore). We defined two main body responsive patches in the superior temporal sulcus (STS) by fMRI. Recordings focused on the posterior one, located at 2-3 mm anterior to the auditory mediatus. Stimuli were shown for 200 ms during a fixation task. Stimulus position was adapted to the receptive field of the neuron. Single neurons in the body patch responded on average significantly stronger to images of bodies (monkey, human, mammal and bird) than to images of other stimulus classes (including faces). Nevertheless, all neurons showed a large difference in responses to different exemplars of the body classes (high within-class selectivity). Cluster analysis of the neural distances between the images based on net spiking responses and high gamma LFP power revealed two main clusters -all bodies (monkeys, humans, mammals, and birds) vs. all other stimuli (mainly faces, objects, fruits). The sculptures were found equally often in both clusters. Lateral to the body patch at the same A/P level, the neurons responded equally strong to bodies and faces, but less to the images of other classes. Cluster analysis based on the responses of those neurons showed 3 main clusters: bodies vs. Faces vs. other inanimate stimuli. In addition, most neurons showed strong selectivity for the orientation of the image. Keywords: Vision, temporal cortex, bodies, Categories, Rhesus Monkey Conference: Belgian Brain Council, Liège, Belgium, 27 Oct - 27 Oct, 2012. Presentation Type: Poster Presentation Topic: Higher Brain Functions in health and disease: cognition and memory Citation: Popivanov ID, Jastorff J, Vanduffel W and Vogels R (2012). Single cell stimulus selectivities in the macaque middle superior temporal sulcus body patch, defined by fMRI. Conference Abstract: Belgian Brain Council. doi: 10.3389/conf.fnhum.2012.210.00095 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 22 Aug 2012; Published Online: 12 Sep 2012. * Correspondence: Mr. Ivo D Popivanov, KU Leuven, Leuven, 3000, Belgium, ivo.popivanov@med.kuleuven.be Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Ivo D Popivanov Jan Jastorff Wim Vanduffel Rufin Vogels Google Ivo D Popivanov Jan Jastorff Wim Vanduffel Rufin Vogels Google Scholar Ivo D Popivanov Jan Jastorff Wim Vanduffel Rufin Vogels PubMed Ivo D Popivanov Jan Jastorff Wim Vanduffel Rufin Vogels Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.