Single‐Cell Motility Rapidly Quantifying Heteroresistance in Populations of Escherichia coli and Salmonella typhimurium

Abstract

Single-Cell Bacterial Motility Rapidly Identifies HeteroresistanceA key issue in the study of antimicrobial resistance is that heterogeneous bacterial populations can display varied responses to antibiotics. In article number 2100123, Giampaolo Pitruzzello, Thomas F. Krauss, and co-workers show that single-cell motility measured in microfluidic arrays of trapped bacteria can rapidly identify heteroresistance in bacterial populations and quantify the minimum inhibitory concentration of antibiotics.