Abstract
AbstractSingle‐cell analysis techniques provide the opportunity to study the cellular heterogeneity that occurs between cells of the same tissue. These methods should ideally be non‐destructive and label‐free to allow long‐term measurements that do not impede with healthy cellular functions. To that end, a miniaturized electrical impedance tomography (µEIT) system is fabricated via rolled‐up nanotechnology to study the electrical properties of individual cells. The tube contains an array of 12 electrodes on its interior wall, and its diameter of ca. 30 µm is tuned to fit the size of a cell. First proof‐of‐concept measurements are carried out with silica and half‐metal coated microparticle phantoms. Additionally, the death of a single HeLa cell is monitored with the µEIT device over time. In the future, the system can be applied to study, e.g. the efficiency of drugs or the biocompatibility of materials on a single‐cell level.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
