Abstract

Single beam acoustic tweezer, a distant cousin of optical tweezer, has been recently experimentally validated. A prerequisite of acoustic tweezer as in optical tweezer is a sharply focused beam with a steep intensity variation within the dimension of a particle. As the frequency of an acoustic beam reaches 100 MHz or higher, the beam diameter approaches cellular level allowing acoustic tweezing or trapping of a cell. Recent experimental results have shown that at 200 MHz it is possible to trap particles as small as 1 μm and red blood cells (RBC). These results along with the experimental arrangement and potential biomedical applications of acoustic tweezer including measuring RBC deformability will be discussed in detail in this talk.

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