Abstract
Two simple, precise, accurate, specific and reproducible spectrophotometric methods have been developed for the simultaneous estimation of Amlodipine Besylate and Perindopril Erbumine in combined tablet dosage form using simultaneous equation and first order derivative methods. In method A (simultaneous equation method) Amlodipine Besylate and Perindopril Erbumine have absorbance maxima at 235 nm and 210 nm respectively in methanol. Method B involves first order derivative spectroscopy, 220 nm was selected for the estimation of Amlodipine Besylate which is zero crossing for Perindopril Erbumine whereas 240 nm selected for the estimation of Perindopril Erbumine which is zero crossing for Amlodipine Besylate. The developed methods were found to be accurate, precise and reproducible and have been validated statistically.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.