Simultaneous Presentation of Conventional and Pigmented Squamous Cell Carcinomas of the Oral Cavity

Abstract

Simultaneous presentation of multiple oral squamous cell carcinomas (OSCCs) is a rare event, with less than 15 cases reported in the literature. We contribute an additional case of simultaneous conventional and pigmented OSCC. A 55-year-old man with a history of tobacco and alcohol consumption presented with 2 simultaneous lesions of unknown evolution—one was an asymptomatic 2-cm ulcer in the left border of the tongue and other was an erythroleukoplakia with pigmented areas measuring 1.5 cm in the right retromolar region. Both lesions were microscopically diagnosed as squamous cell carcinoma, the latter being classified as the pigmented variant of OSCC. The patient is stable, with no signs of recurrence 6 months after oncologic surgical treatment. Clinicians should consider the possibility of simultaneous occurrence of multiple OSCCs.