Abstract
Two simple spectrophotometric methods for the determination of aceclofenac and paracetamol in tablets have been developed. First method is based on the additivity of absorbances. Second method is based on the determination of graphical absorbance ratio at two selected wavelengths; one being the isoabsorptive point for the two drugs (230 nm) and the other being the absorption maximum of paracetamol (256 nm). Beer-Lambert's law is obeyed for both the drugs in the concentration range 1-10 μg/mL. Both the methods were found to be simple, rapid, and accurate and can be adopted in routine analysis of drugs in formulations.
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