Abstract
The fabrication of an electrochemical sensor based on an iron oxide/graphene modified glassy carbon electrode (Fe3O4/rGO/GCE) and its simultaneous detection of dopamine (DA) and ascorbic acid (AA) is described here. The Fe3O4/rGO nanocomposite was synthesized via a simple, one step in-situ wet chemical method and characterized by different techniques. The presence of Fe3O4 nanoparticles on the surface of rGO sheets was confirmed by FESEM and TEM images. The electrochemical behavior of Fe3O4/rGO/GCE towards electrocatalytic oxidation of DA was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) analysis. The electrochemical studies revealed that the Fe3O4/rGO/GCE dramatically increased the current response against the DA, due to the synergistic effect emerged between Fe3O4 and rGO. This implies that Fe3O4/rGO/GCE could exhibit excellent electrocatalytic activity and remarkable electron transfer kinetics towards the oxidation of DA. Moreover, the modified sensor electrode portrayed sensitivity and selectivity for simultaneous determination of AA and DA. The observed DPVs response linearly depends on AA and DA concentration in the range of 1–9 mM and 0.5–100 μM, with correlation coefficients of 0.995 and 0.996, respectively. The detection limit of (S/N = 3) was found to be 0.42 and 0.12 μM for AA and DA, respectively.
Highlights
Dopamine (DA) is one of the most important catecholamine neurotransmitters which are produced in the adrenal glands and several area of the brain
Based on the above facts, we report a simple, cost-effective and green approach for the preparation of magnetite graphene (Fe3O4/reduced graphene oxide (rGO)) nanocomposites by using in-situ one-step chemical method at room temperature
The synthesis pathway of Fe3O4/rGO nanocomposites involved the redox reaction between the graphene oxide (GO)
Summary
Dopamine (DA) is one of the most important catecholamine neurotransmitters which are produced in the adrenal glands and several area of the brain. Electrochemical sensors are a preferred alternative method because of their simple operation, fast response, time savings, low-cost, high-sensitivity, excellent selectivity and real-time detection. It is difficult to selectively sense the DA in the presence of high concentration levels of AA, because these two species are sharing nearly the same oxidation potential on the bare electrode, which results rather poor selectivity and sensitivity of DA detection [7]. The chemical modification of electrode surfaces has been developed to enhance the sensitivity and selectivity of electrochemical sensors. Based on the above facts, we report a simple, cost-effective and green approach for the preparation of magnetite graphene (Fe3O4/rGO) nanocomposites by using in-situ one-step chemical method at room temperature. The fabricated electrochemical sensor has exhibited rapid response, selectivity and sensitivity towards the determination of DA in the presence of AA
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