Abstract
A simple and reliable method for simultaneous determination of purine and pyrimidine (guanine, adenine, thymine and cytosine) was developed at poly(3,4-ethylenedioxythiophene)/electro-deposited graphene modified glassy carbon electrode (PEDOT/GR/GCE). Scanning electron microscopy and electrochemical impedance spectroscopy were used to examine the morphology and interface property of PEDOT/GR film. Differential pulse voltammetry was utilized to investigate the electrochemical behavior of DNA bases in 0.1M PBS (pH 7.4). The results showed that the peaks of four bases were well separated. The proposed sensor exhibited low detection limit, high sensitivity and wide linear range for simultaneous detection of four DNA bases, with high stability.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
