Simultaneous colonization by gram-negative hospital pathogens

Abstract

Objectives . Assessment of the probability of simultaneous infection with two or more pathogens of clinical substrates of transplant patients. Materials and methods . The retrospective analysis of bacteriological studies of clinical isolates among transplant patients operated from January to July 2020 is performed. This study included 93 patients. Results and discussion . Тhe risk of bacterial complications in the postoperative period is associated with representatives of the gram-negative pathogens Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. All the studied strains were resistant to antibiotics. A significant number of coinfections with two or three pathogens cases were recorded in the current period – 20.4 %. For the two and more pathogens’ colonization the highest mortality rate is shown, 42.1 %. Conclusions . Modern epidemiological feature is the Acinetobacter baumannii predominance among the microflora of transplant patients. It has been shown that the incidence of co-colonization by ≥ 2 different gram-negative pathogens is significant and increases the mortality rate.