Abstract
The application of mixture analysis techniques to liquid chromatography-diode array detector (LC-DAD) data can be hampered by instrumental artefacts. If not properly accounted for, these artefacts may create major problems in the interpretation of the results by introducing additional factors in the analysis that can be difficult to distinguish from minor chemical components. In this paper, we show how the main sources of instrumental errors can be identified and how their effect can be mimicked by a specifically designed simulation procedure. Such realistic simulations are then successfully used to anticipate the expected response for an homogeneous peak even under non-ideal conditions, and hence to facilitate unequivocal interpretation of results.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
