SIMULATION STUDY OF SELECTIVE CEREBRAL PERFUSION SYSTEM WITH SINGLE CENTRIFUGAL PUMP

Abstract

Background: We successfully developed a simple and safety non-roller extra-corporeal circulation system (NRECC). In aortic arch operation, more than two pumps are generally used for usual perfusion and selective cerebral perfusion (SCP). We newly developed a pressure-dependent perfusion system for SCP. The system was developed based on the NRECC we developed and was operated with a single centrifugal pump (Figure). Method: The cerebral perfusion line was branched from the main perfusion line. The perfusion pressure was regulated with a tube occluder. Glycerin was added to the priming solution for a similar viscosity to blood.FigureIn this study, one 15F and two 12F cannulae were used for SCP. After load was changed from 30 to 80 mmHg, and the pressure of the SCP line was increased from 80 to 200 mmHg and flow volume were measured. Results When after load was set at 50mmHg, according to the change of the perfusion pressure, flow volume of 15F cannula increased from 280 to 950 ml/min.FigureIn the same condition, flow volume of 12F cannula increased from 160 to 560 ml/min. Conclusions: The flow volume of the SCP lines was sufficiently obtained under the SCP line pressure over 80mmHg. These suggested that aortic arch operation is possible using this SCP system.