Abstract

Abstract The dynamic aortic valve (DAV) is a new left ventricular assist device, a micro-axial blood pump implemented at the position of the aortic valve, pumping blood from the left ventricle into the aortic artery. The present dynamic aortic valve operated at 7 different rotation speeds, ranging from 3000 r min (speed 1) to 9000 r min (speed 7). Because in vivo experiments need a lot of live animals and take a long period of time, modeling and simulation have been widely used a simulate and analyze hydra-dynamic property of the DAV and its assisting effects. With the measurements from the mock circulatory loop, a mathematic model of the DAV is established and embedded into the previously developed canine circulatory system. Using the model, the effect of the DAV on the failing heart at each rotation speed level is investigated. The vital cardiac variables are compared with in vivo experimental results, which are in good agreement with an acceptable different mostly 15%. The establishment of the DAV mode...

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