Abstract
This paper mainly describes the way to get the volume model of damaged region according to the simulation on temperature field of radiofrequency ablation lesion system in curing Parkinson's disease based on finite element method. This volume model reflects, to some degree, the shape and size of the damaged tissue during the treatment with all tendencies in different time or core temperature. By using Pennes equation as heat conduction equation of radiofrequency ablation of biological tissue, the author obtains the temperature distribution field of biological tissue in the method of finite element for solving equations. In order to establish damage models at temperature points of 60°C, 65°C, 70°C, 75°C, 80°C, 85°C and 90 °C while the time points are 30s, 60s, 90s and 120s, Parkinson's disease model of nuclei is reduced to uniform, infinite model with RF pin at the origin. Theoretical simulations of these models are displayed, focusing on a variety of conditions about the effective lesion size on horizontal and vertical. The results show the binary complete quadratic non-linear joint temperature-time models of the maximum damage diameter and maximum height. The models can comprehensively reflect the degeneration of target tissue caused by radio frequency temperature and duration. This lay the foundation for accurately monitor of clinical RF treatment of Parkinson's disease in the future.
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