Abstract
A mathematical model of cardiac nodal cells was used to study certain aspects of the phenomenon of concealed conduction. This model consists of two nonlinear first order differential equations which were programmed on an analog computer. A particular feature of the model is the possibility of obtaining graded responses by means of a pulse stimulus occurring during the period of relative refractoriness following a spike discharge. The fluctuations in excitability accompanying such graded responses can account for a delayed reduction in the excitability of the spike generating mechanism. The results of the simulation study suggest that concealment of atrial impulses within the A-V node may be the result of dynamic excitability variations occurring in a region of the A-V node where a discontinuous excitability characteristic exists.
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