Abstract
This study provides a detailed explanation of a regulating mechanism of the blood glucose levels by an agent-based software engineering tool. Repast Simphony which is used in implementation of this study is an agent-based software engineering tool based on the object-oriented programming using Java language. Agent-based modeling and simulation is a computational methodology for simulating and exploring phenomena that includes a large set of active components represented by agents. The agents are main components situated in space and time of agent-based simulation environment. In this study, we present hormonal regulation of blood glucose levels by our improved agent-based control mechanism. Hormonal regulation of blood glucose levels is an important process to maintain homeostasis inside the human body. We offer a negative feedback control mechanism with agent-based modeling approach to regulate the secretion of insulin hormone which is responsible for increasing the blood glucose levels. The negative feedback control mechanism run by three main agents that interact with each other to perform their local actions in the simulation environment. The result of this study shows the local behavior of the agents in the negative feedback loop and illustrates how to balance the blood glucose levels. Finally, this study which is thought a potential implementation of agent-based modeling and simulation may contribute to the exploration of other homeostatic control systems inside the human body.
Highlights
Human physiology includes fundamental systems that control the vital functions and processes
We modeled and simulated hormonal regulation of blood glucose level using the agentbased modeling and simulation (ABMS) technique
We introduce and visualize the process by which the blood glucose levels are regulated by negative feedback control mechanism [10]
Summary
Human physiology includes fundamental systems that control the vital functions and processes. The endocrine system plays an active role for maintaining homeostasis It is known as the hormonal system, which basically regulates metabolic functions such as appetite, mood, sexual, reproduction, growth and development, sleep cycles, and more [3]. We modeled and simulated hormonal regulation of blood glucose level using the agentbased modeling and simulation (ABMS) technique. This chapter is organized as follows: Section 2 gives a brief overview of hormonal regulation of blood glucose levels; Section 3 presents the method of this study which offers an agent-based control system; Section 4 provides implementation of case study involving experimental results; Section 5 explains some limitations of this study, and Section 6 concludes with a brief summary of this study
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